The number of breast cancer cases has almost doubled since 1970, but the treatment and observation measures have been so effective that the death rate is steadily decreasing. It is however very important to reduce risk factors so that few cancers begin, and today’s modern genetic diagnostics provides opportunities to do this. Even people who have already been diagnosed with breast cancer will benefit from knowing the various risk factors that they are subject to, in order to eliminate as many risks as possible. Therefore, it is important to know one’s own genetic predispositions and to make specific lifestyle changes that will maximize the opportunity for a healthy life.
Most cases of breast cancer are caused by an unfortunate interaction of genetic predisposition and environmental triggers. Women who have a high risk of breast cancer are at an even higher risk if they follow an unhealthy lifestyle. It is important for women to know their genetic risk, and if necessary to take preventive measures and/or make lifestyle changes.
Although some cases of breast cancer occur sporadically with age, it is estimated that genetic predisposition is responsible for about 58% of breast cancer cases. Ten genes associated with breast cancer can now be tested for traits that affect an individual’s risk of disease. A person with a strong genetic predisposition to cancer can reduce their overall risk by adopting a balanced diet and avoiding other risk factors. Also, regular checkups will allow the early detection of the disease and timely treatment.
Relevant genes for breast cancer
Several genetic variations have been identified, which taken individually slightly increase or decrease the risk of breast cancer. Taken together, they have a significant impact on risk probability. The analysis of relevant genetic variations came to the following conclusion:
LEGEND: rsNCBl = description of examined genetic variation, POLYMORPHlSM = a form of the genetic
variation, GENOTYPE = personal analysis result
Summary of effects
Here you can see a summary of the impact your genetic variations have on your health and your
- Your risk of developing breast cancer is lower than the population average.
- Caffeine will not reduce the development of breast cancer
Based on your genetic profile, you have no higher risk for breast cancer than the average person.
While you do not have a high risk of developing breast cancer, some people with no genetic risk do develop cancer. Therefore, you should follow the usual preventive measures and self-examination. Every person should take the following steps to reduce the risk of breast cancer:
Lifestyle plays an important role in the development of breast cancer, and a significant amount of the risk of cancer is based on specific behavior choices. You can take several steps to reduce your risk of breast cancer.
- Excess weight increases the risk of breast cancer2.5 times. Keeping a healthy weight is key to reducing your risk for breast cancer along with many other diseases.
- Tobacco smoking is an equally important risk factor that increases the risk of breast cancer by about 30%, in addition to the many other health problems it causes. Consuming more than 20g of alcohol (about 120 ml of red wine, or one glass) increases breast cancer risk by about30% and should, therefore, be avoided.
- Vitamin D deficiency is a significant risk factor for breast cancer. Vitamin D is normally produced in the presence of UV-B rays from the sun, so deficiencies are more common in countries with less sunlight or in people who are indoors most of the time. This deficiency is associated with a variety of cancer forms, and so an adequate uptake of vitamin D is highly recommended. Exercise outdoors as much as possible and make sure your diet contains sufficient quantities of vitamin D. Salmon, tuna and mackerel are some of the foods containing vitamin D. However, it is generally advisable to ensure adequate vitamin supplements.
Early detection plays a significant role in every type of cancer, which is why women are encouraged to go to annual breast cancer checkups. Women with your genetic profile should
follow the following routine checkups:
- From the age of 20, go to annual breast examinations.
- From the age of 20, perform regular self-examinations of the breast tissue.
- Examine the tissue of your breasts for hard inclusions.
- should you detect a hard inclusion, talk to your doctor about it immediately.
- From the age of 40, have mammography performed every one to 2years.
In this way, a possible cancer is detected immediately and treated in time.
Effect on relevant medication
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